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In addition, by carefully excluding patients with preexisting depression or recent antidepressant use, the design minimizes potential confounding by indication [] The clinical implications of this study are multifaceted

Western blot analysis illustrated that sulforaphane increased the expression of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), heme oxygenase-1 (HO-1) and NAD(P)H quinone oxidoreductase (NQO1), the latter two of which are anti-oxidative enzymes